About
Patrick Girondi
Photography by:Â Luigi Porzia
PATRICK GIRONDI, originally from the South Side of Chicago, is an Italian and American internationally acclaimed singer-songwriter, author, producer, and founder of San Rocco Therapeutics (SRT).
SRT focuses on bringing a safe and accessible cure to Sickle Cell Disease and Thalassemia patients.
Literary Achievements
A Wall Street Journal bestselling author, Girondi has written Flight of the Rondone, New City, Blind Faith, Faded Genes, and Chivalry among others. His five most recent books were published by the cutting edge publisher Skyhorse. Skyhorse has also released audiobooks, read and performed by Girondi and a small cast of actors, for all published works.
Girondi has additionally completed five screenplays in English and four in Italian. He has collaborated with L.A. screenwriter P.G. Cuschieri and his script Resurrection was made into a movie in 2026, featuring Joe Mantegna, Brian Connors, and Ronnie Marmo.
Patrick Girondi & the Orphan’s Dream/Music Career
In 2004, Patrick Girondi & the Orphan’s Dream band published its first CD, ‘Orphanâs Soul.’ All of the albums explore orphan disease (rare disease) and how it has affected the lead singer, Patrick Girondi’s life. The band has written all 80 of their published songs.
The fifth album, “Orphanâs Return,” was released days before the culmination of Girondi’s 5-year pharmaceutical court battle. As the album’s name hints, the verdict allowed Girondi to return to his work of curing rare diseases.
Girondiâs music has been featured in the Award-winning Italian film Focaccia Blues (2009) and has also been featured in Ed Asner: Unscripted (2022); Il Settimo Giocatore (2022); and Resurrection (2026). Patrick Girondi & the Orphanâs Dream Band has been featured dozens of times in Italian newspapers as well as on television in New York, Chicago, and Italy.
Patrick Girondi has performed with Italian acts, The Pooh and Renzo Arbore. He has performed at the Chicago Poor Man Blues Fest in Washington Park with Coco Taylor, and Ronnie Lee Graham; the Harris Theater in Chicago; and the Umbria Jazz Festival. In 2024, Girondi performed at the Tiny Room in Los Angeles with Greg Spero, Joe Cleveland, Devon âStixxâ Taylor, and Alec Lehrman. In 2023, Patrick Girondi & the Orphanâs Dream performed at the world-famous Grotte di Castellana in Bari, Italy.
Film and Media Recognition
In 2026, Girondi completed the movie version of his script Resurrection, starring Joe Mantegna, Brian Connors, and Ronnie Marmo. Resurrection is the story of Patrick Girondi and his son Rocco, embodying the intersection of hope, sacrifice, and the relentless pursuit of justice and healing in the face of adversity.
In 2025, Patrick Girondi was interviewed by Jan Jekielek on American Thought Leaders in a segment titled How I Discovered a Possible Cure for My Sonâs Incurable Disease: Patrick Girondi. He was interviewed earlier in the year on the podcast Soft White Underbelly by Mark Laita in a broadcast titled Fighting Big Pharma To Save My Sonâs Life-Patrick Girondi.
Photography by: Antonio Sansone